This international journal publishes original articles from a wide variety of interdisciplinary perspectives concerning the theory and practice of medical artificial intelligence. Particular attention is given to AI-based clinical decision-making, medical knowledge engineering, knowledge-based systems in medical education and research, intelligent medical information systems, intelligent databases, books, and libraries, intelligent devices and instruments, medical AI tools, reasoning and metareasoning in medicine, and methodological, philosophical, ethical and social issues of AI in medicine.